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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CKB
All Species:
50.91
Human Site:
Y174
Identified Species:
80
UniProt:
P12277
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12277
NP_001814.2
381
42644
Y174
G
D
L
A
G
R
Y
Y
A
L
K
S
M
T
E
Chimpanzee
Pan troglodytes
XP_510185
464
51502
Y257
G
D
L
A
G
R
Y
Y
A
L
K
S
M
T
E
Rhesus Macaque
Macaca mulatta
XP_001112108
381
42634
Y174
G
D
L
A
G
R
Y
Y
A
L
K
S
M
T
E
Dog
Lupus familis
XP_537561
394
44036
Y187
G
D
L
A
G
R
Y
Y
A
L
K
S
M
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q04447
381
42695
Y174
G
D
L
S
G
R
Y
Y
A
L
K
S
M
T
E
Rat
Rattus norvegicus
P07335
381
42707
Y174
G
D
L
S
G
R
Y
Y
A
L
K
S
M
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508143
326
36755
G161
R
D
W
P
D
G
R
G
I
W
H
N
D
N
K
Chicken
Gallus gallus
P05122
381
42852
Y174
G
D
L
K
G
K
Y
Y
A
L
R
N
M
T
D
Frog
Xenopus laevis
NP_001080363
376
42223
Y169
G
D
L
K
G
K
Y
Y
A
L
N
S
M
T
E
Zebra Danio
Brachydanio rerio
NP_775329
381
42865
Y174
G
D
L
K
G
K
Y
Y
A
L
K
D
M
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48610
356
39848
Y168
G
E
L
K
G
K
F
Y
P
L
T
G
M
E
K
Honey Bee
Apis mellifera
O61367
355
39990
Y167
G
E
L
K
G
T
F
Y
P
L
T
G
M
S
K
Nematode Worm
Caenorhab. elegans
Q27535
360
40364
Y172
P
E
L
K
G
T
Y
Y
P
L
T
G
M
D
E
Sea Urchin
Strong. purpuratus
P18294
1174
130851
Y962
G
P
L
K
G
K
Y
Y
P
L
T
G
M
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169054
381
42707
Y174
G
D
L
S
G
R
Y
Y
A
L
K
S
M
T
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.9
99.2
94.4
N.A.
96.5
96.5
N.A.
77.9
90.5
83.1
85.8
N.A.
42.7
40.9
37.7
22.4
Protein Similarity:
100
82.1
100
95.9
N.A.
98.6
98.4
N.A.
83.7
96.3
92.3
93.1
N.A.
59
58.7
55.9
28.1
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
6.6
66.6
80
80
N.A.
40
40
46.6
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
93.3
86.6
86.6
N.A.
66.6
66.6
53.3
66.6
Percent
Protein Identity:
N.A.
96.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
98.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
100
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
27
0
0
0
0
67
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
74
0
0
7
0
0
0
0
0
0
7
7
7
14
% D
% Glu:
0
20
0
0
0
0
0
0
0
0
0
0
0
7
67
% E
% Phe:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% F
% Gly:
87
0
0
0
94
7
0
7
0
0
0
27
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% I
% Lys:
0
0
0
47
0
34
0
0
0
0
54
0
0
0
20
% K
% Leu:
0
0
94
0
0
0
0
0
0
94
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
94
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
7
14
0
7
0
% N
% Pro:
7
7
0
7
0
0
0
0
27
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
47
7
0
0
0
7
0
0
0
0
% R
% Ser:
0
0
0
20
0
0
0
0
0
0
0
54
0
7
0
% S
% Thr:
0
0
0
0
0
14
0
0
0
0
27
0
0
74
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
80
94
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _